Key MLB Matchups and Moneyline Picks for Sunday, March 29

Sunday’s MLB slate features an exciting 12-game lineup, showcasing pitchers who are grappling with command issues early in the season. With so much action on the horizon, let’s dive into the top moneyline picks for March 29.

Grant Holmes possesses a powerful arm, but he faces a formidable challenge against an Atlanta Braves lineup that showcased its offensive prowess by scoring six runs on Opening Day. Seth Lugo, who has struggled this spring, will need to find his rhythm quickly to keep the Braves at bay.

Meanwhile, Shane Baz enters the day riding the momentum of a career-best season, while Minnesota’s Bailey Ober seeks redemption after a rough spring. Given Ober’s difficulties, siding with Baz and the Baltimore Orioles seems like a prudent choice.

In another matchup, Jesus Luzardo stands out as the superior pitcher, and the Philadelphia Phillies will look to capitalize on Mackenzie Gore’s struggles this spring. Gore’s inability to consistently get outs makes him a risky option against a potent Phillies lineup.

Eric Lauer enjoyed the best season of his career last year, but he now faces off against Luis Morales, who has had a challenging spring. Morales will need to rise to the occasion on the road against a Blue Jays offense led by Vladimir Guerrero Jr.

Connolly Early has a lively arm but has also faced challenges this spring. Rhett Lowder, who missed an entire season, struggled as well, indicating that we might see both bullpens early in this matchup, with Boston’s bullpen appearing to hold the edge.

The Colorado Rockies enter this game with the league’s worst record from last season, facing a promising Miami Marlins team. Young pitcher Max Meyer has shown promise this spring, positioning Miami as the favorites with their superior pitching.

Nolan McLean, who impressed in 2025, brings that momentum into this matchup, while Carmen Mlodzinski’s command issues could prove costly against a New York Mets lineup that exploded for 11 runs on Opening Day.

As Tatsuya Imai makes his highly anticipated MLB debut, he will encounter a swinging Angels offense that has started the season strong. Jack Kochanowicz’s command problems raise concerns, making it difficult to trust him against the powerful Houston lineup.

The Chicago White Sox’s pitching staff allowed a staggering 14 runs on Opening Day, putting pressure on lefty Anthony Kay, who has also struggled with command this spring. He faces a Brewers lineup that should provide enough run support for Brandon Sproat to secure a comfortable win.

Steven Matz, now facing his former team, boasts commendable command, though he has a mixed record on the road at 33-32. Dustin May, armed with electric stuff, is expected to receive ample run support from a hot Cardinals lineup.

Jake Irvin’s solid spring performance is overshadowed by concerns about his susceptibility to home runs, especially on a breezy day. Shota Imanaga, with a strong track record against the Nationals, looks to lead the Cubs to victory, bolstered by a supporting cast of bats.

Finally, Slade Cecconi enters this matchup with a strong spring behind him. Despite facing a challenging Seattle lineup, he may find enough run support, as Emerson Hancock’s command issues could be a deciding factor.

Note: This recap is an independently written summary based on publicly available reporting.