Week 2 NFL Showdowns: Highlights and Betting Insights

Week 2 of the NFL season started with a surprise as the Buffalo Bills, seen as the underdogs, triumphed over the slight favorites, Miami Dolphins, with a score of 31-10 on Thursday’s AFC East clash. The week will wrap up with Monday Night Football featuring Jalen Hurts and his Philadelphia Eagles in their North American season opener, squaring off against the Atlanta Falcons.

The Las Vegas Raiders, labeled as the week’s biggest underdogs, are set to face the Baltimore Ravens on the road, with the betting line continuing to fluctuate. The game with the highest total is the Tampa Bay Buccaneers vs. Detroit Lions, scheduled for Sunday afternoon in Detroit.

The Sunday night game sees C.J. Stroud and his Houston Texans ceding 6.5 points to Caleb Williams and his Chicago Bears. Please note, odds are correct at the time of publication, for the most up-to-date odds, check your favorite sportsbook.

2024 NFL Week 2 Odds, Spreads, and Totals

San Francisco 49ers vs. Minnesota Vikings

Starting at 1:00 PM ET, Sunday on CBS, the 49ers, favored by 5, are up against the Vikings. The money line stands at 49ers (-230); Vikings (+195) with a total of 46.5, which opened at 46.5.

Los Angeles Chargers vs. Carolina Panthers

The Chargers, favored by 7, will take on the Panthers at 1:00 PM ET, Sunday on CBS. The betting line opened at Chargers -3. The money line is Chargers (-230); Panthers (+195), with a total of 39.5, down from an opening of 42.

Indianapolis Colts vs. Green Bay Packers

The Colts, with a slender advantage of 1.8, will face the Packers at 1:00 PM ET, Sunday on FOX. The money line is Colts (-150); Packers (+130), with a total of 40.5, down from an opening of 47.5.

New York Giants vs. Washington Commanders

The Commanders, favored by 4.3, will take on the Giants at 1:00 PM ET, Sunday on FOX. The money line is Giants (+105); Commanders (-125), with a total of 43.5, up from an opening of 42.5.

More NFL Week 2 Matchups and Betting Insights

Various other matchups are set to take place throughout Sunday, including the New Orleans Saints vs. Dallas Cowboys, Cleveland Browns vs. Jacksonville Jaguars, New York Jets vs. Tennessee Titans, Tampa Bay Buccaneers vs. Detroit Lions, Las Vegas Raiders vs. Baltimore Ravens, Seattle Seahawks vs. New England Patriots, Los Angeles Rams vs. Arizona Cardinals, Cincinnati Bengals vs. Kansas City Chiefs, and the Pittsburgh Steelers vs. Denver Broncos.

The week concludes with the Chicago Bears squaring off against the Houston Texans on Sunday night and the Atlanta Falcons facing the Philadelphia Eagles on Monday night.

Stay tuned for all the exciting NFL action, unexpected upsets, and insightful betting odds as the games unfold.